13 träffar

DrugNon-selective COX inhibitor, propionic acid derivative
Ibuprofen

…Sweden and the one with the least cardiovascular risk at a low dose. A short half-life of around 2 hours means the effect arrives…

DrugHMG-CoA reductase inhibitor
Atorvastatin

…Atorvastatin Krka HMG-CoA reductase inhibitor High-intensity statin with a long half-life, allowing it to be taken at any time of day unlike…

DrugTricyclic antidepressant
Amitriptyline

…for depression in contemporary practice — its role today is neuropathic pain and prophylaxis for migraine and chronic tension-type headache, at doses well below the…

DrugThiazide diuretic
Bendroflumethiazide

…thiazide diuretic for hypertension. The key point is that the dose–response curve for blood pressure flattens already at 2,5 mg, while the adverse…

DrugLow molecular weight heparin
Dalteparin

…confusing the two is the most common dosing error. Unlike unfractionated heparin, dalteparin is eliminated renally, so at eGFR below 30 ml/min the effect…

DrugNon-selective COX inhibitor with COX-2 predominance, phenylacetic acid derivative
Diclofenac

…the class — the increase in risk for myocardial infarction, stroke, and heart failure resembles that of selective COX-2 inhibitors and is seen already at…

DrugSynthetic catecholamine, β₁-agonist (inotropy)
Dobutamine

…is the pump and not vascular tone. Strong β₁ effect with marked β₂ effect means that stroke volume increases while systemic vascular resistance falls at…

DrugSelective serotonin reuptake inhibitor (SSRI)
Escitalopram

…efficacy but the heart: a dose-dependent QT prolongation was identified, and the maximum dose has since been capped at 20 mg for adults and…

DrugLoop diuretic
Furosemide

…curve, not a line: below the threshold nothing happens, and in renal failure the threshold dose must be raised to achieve any effect at all.

DrugSpecific antidote to dabigatran, humanised Fab fragment
Idarucizumab

…in plasma falls by over 99 per cent directly after the infusion. The specificity is also the limitation — it does nothing at all against apixaban…

DrugKompetitiv opioidreceptorantagonist
🇸🇪 Naloxone

…är att återställa andningen, inte vakenheten — därför titreras små doser, 0,04–0,4 mg åt gången, tills patienten andas tillräckligt. Den korta halveringstiden är…

DrugIndirect thrombin and factor Xa inhibitor via antithrombin
Heparin (unfractionated)

…become necessary at short notice. The disadvantages are continuous infusion, an unpredictable dose–response relationship due to binding to plasma proteins, and the risk of…

DrugElectrolyte concentrate for potassium replacement
Potassium chloride

…concentrate for potassium replacement Potassium deficiency is corrected slowly because extracellular potassium is only two per cent of the body's total potassium store — the…