…Sjögren syndrome, gout and antiphospholipid syndrome (APS). Collectively, these disorders are associated with excess cardiovascular disease (CVD), although the cardiovascular phenotype varies substantially between diseases…

…Antiphospholipid syndrome, particularly triple positive disease or after an arterial event, where DOACs have proved inferior. Atrial fibrillation with marked renal failure or on dialysis…

…mmHg for 15 minutes, or a need for a vasopressor), obstructive shock or cardiac arrest with suspected pulmonary embolism. Urgent bedside echocardiography, looking for right…