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Sinus node dysfunction (SND) and sick sinus syndrome (SSS)

…article. A rehearsal follows. Reversible causes of sinus node dysfunction Age related degenerative disease (development of fibrosis) of the sinoatrial node. Myocardial ischemia/infarction. Perimyocarditis…

🟠 HCM Risk-SCD Calculator

[calc_hcmrisk] Predicting Sudden Cardiac Death in Hypertrophic Cardiomyopathy (HCM) Hypertrophic Cardiomyopathy (HCM) is a genetic cardiomyopathy characterized by left ventricular hypertrophy. It is the…

Familial Hypercholesterolaemia: Diagnosis, Cascade Screening and Treatment

…miscellaneous conditions Definition and pathophysiology Familial hypercholesterolaemia (FH) is an inherited disorder characterized by persistently elevated plasma low density lipoprotein cholesterol (LDL C) from early…

Heart Failure with Preserved Ejection Fraction (HFpEF)

…differences in cardiovascular aging, including smaller ventricular cavities, greater age related vascular stiffening, and distinct microvascular responses to systemic inflammation [7] . The dominant risk factors…

Cardiovascular Risk in Women: Sex-Specific Factors

…lifetime burden of hypertension. Hypertension becomes more prevalent in women than men after approximately 65 years of age. Hypertension related left ventricular hypertrophy, concentric remodelling…

Hypertrophic Cardiomyopathy (HCM) & Hypertrophic Obstructive Cardiomyopathy (HOCM)

…pronounced than the load could reasonably explain). The probability of hypertrophic cardiomyopathy is inversely related to age, such that the younger the patient presenting with…

Preeclampsia and Hypertensive Pregnancy Disorders as Future Cardiovascular Risk

…morbidity and mortality. Their incidence has increased in parallel with older maternal age at first childbirth and the rising prevalence of obesity. Gestational hypertension is…

STEMI: Primary PCI and System-of-Care Time Targets

…of ischaemic symptoms. The immediate pathophysiological objective is restoration of blood flow to the infarct related myocardial territory and limitation of infarct size. The extent…

A Novel Familial Cardiac Arrhythmia Syndrome Identified Using ECG

…fibrillation arrests and moderate left ventricular dysfunction. This patient died at age 17 years due to complications related to his arrhythmia. His father and uncle…

Exercise Electrocardiographic Testing: Indications, Limitations and Interpretation

…tolerance Reproduction and characterization of symptoms Heart rate and blood pressure responses to exercise Detection of exercise induced arrhythmias Identification of exercise related ST segment…

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