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🟠 Clevidipine

…egg), of which the maximum dose per 24 hours is 1000 mL. Adverse effects Headache. Nausea. Fever. Atrial fibrillation. Worsening of heart failure. Caution • Used…

Refractory Angina: Options When Standard Therapy Fails

…Functional limitation and effect on activities of daily living. Workload or exertion required to provoke symptoms. Response to current antianginal therapy. Adverse effects that restrict…

Ivabradine: Indications, Dosing and Heart-Rate Targets

…portion of its transmembrane pore, ivabradine reduces the slope of diastolic depolarisation and produces a dose dependent reduction in sinus rate. Its principal therapeutic distinction…

Levosimendan (Simdax, Simendan) in acute heart failure

…blood pressure lowering effect persists for a duration of 3 to 4 days post infusion, thereby providing extended therapeutic benefits. 2 Infusion of levosimendan can…

Dual Antiplatelet Therapy Duration After Acute Coronary Syndromes and Elective Percutaneous Coronary Intervention

…may be used as a de escalation strategy after a period of DAPT. The therapeutic objective is to reduce coronary thrombotic events without exposing the…

🟠 Hypertensive emergency (crisis) - Drugs, doses & management

…The desired time to action, contraindications and risk of adverse effects should guide the choice of agent. Calcium channel blockers (CCB) Clevidipine Drug Clevidipine Brand…

Hypertensive emergency (crisis)

…The desired time to action, contraindications and risk of adverse effects should guide the choice of agent. Calcium channel blockers (CCB) Clevidipine Drug Clevidipine Brand…

PCSK9 Inhibitors: Indications, Efficacy and Access

…clearance of circulating LDL cholesterol (LDL C). Increased PCSK9 activity therefore contributes to higher LDL C concentrations. The genetic evidence provides the rationale for therapeutic…

Digoxin - ECG changes, arrhythmias, conduction defects & treatment

…digoxin treatment. Adverse effects of digoxin The incidence of adverse drug reactions is high, owing to the narrow therapeutic index of the drug. Digoxin is…

Type 2 Diabetes and Cardiovascular Risk Management

…arrhythmogenesis through diabetic neuropathy and adverse metabolic effects, independently of coexisting CAD, previous myocardial infarction or HF. Nevertheless, the risk of arrhythmia and sudden cardiac…

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