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Ivabradine: Indications, Dosing and Heart-Rate Targets

Cardiology Pharmacology & dosing Definition and pharmacological basis Ivabradine is a selective inhibitor of the If, or “funny,” current in sinoatrial node pacemaker cells. This current…

🟠 Clevidipine

…egg), of which the maximum dose per 24 hours is 1000 mL. Adverse effects Headache. Nausea. Fever. Atrial fibrillation. Worsening of heart failure. Caution • Used…

🟠 Hypertensive emergency (crisis) - Drugs, doses & management

…The desired time to action, contraindications and risk of adverse effects should guide the choice of agent. Calcium channel blockers (CCB) Clevidipine Drug Clevidipine Brand…

Hypertensive emergency (crisis)

…The desired time to action, contraindications and risk of adverse effects should guide the choice of agent. Calcium channel blockers (CCB) Clevidipine Drug Clevidipine Brand…

Pharmacologic agents in myocardial perfusion imaging

…coronary vasodilation. This selectivity minimizes activation of A1, A2B, and A3 receptors, which are associated with adverse effects such as bronchoconstriction and atrioventricular block. Adenosine…

Inotropes and vasopressors: doses, indications, contraindications and effects

…of each drug according to its vasoconstrictor effect (vertical axis) and its positive inotropic effect (horizontal axis). Grey = pure vasopressors, orange = phosphodiesterase inhibitors…

🟠 Phentolamine

…crisis. Mechanism of action Phentolamine is a non selective alpha adrenergic blocker. Phentolamine reduces blood pressure while increasing catecholamine activity. Effects Primarily causes afterload reduction…

Dual Antiplatelet Therapy Duration After Acute Coronary Syndromes and Elective Percutaneous Coronary Intervention

…with increased risk of major adverse cardiovascular events (MACE) and stent thrombosis. Premature DAPT interruption is described as the strongest predictor of stent thrombosis in…

Levosimendan (Simdax, Simendan) in acute heart failure

…and valvular function. Levosimendan drug is generally well tolerated. Severe adverse effects are less common. Levosimendan may be administered simultaneously with milrinone. The drugs can…

Type 2 Diabetes and Cardiovascular Risk Management

…selection of glucose lowering therapies with demonstrated cardiovascular effects. Diabetes may also contribute to arrhythmogenesis through diabetic neuropathy and adverse metabolic effects, independently of coexisting…

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