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Type 2 Diabetes and Cardiovascular Risk Management

…is mediated by the combined effects of hyperglycaemia, hypertension, dyslipidaemia, obesity, smoking and other conventional risk factors, together with diabetes specific vascular and metabolic abnormalities…

ACE Inhibitor Cough and Angioedema: Practical Management

…their use is limited by specific adverse effects. Most of these adverse events are related to the suppression of the renin angiotensin aldosterone system (RAAS)…

Edrophonium test

…obstruction of the bowel or the urinary tract. Marked bradycardia, sick sinus syndrome or high grade AV block without pacemaker protection. Asthma and other marked…

Adenosine for tachyarrhythmias (AVNRT, AVRT, NCT)

…is not an established drug interaction. The half life of adenosine is 8 seconds. Adverse effects are therefore very brief. Indications Paroxysmal supraventricular tachycardia (PSVT…

Hypertensive crisis: drugs and doses

…hypertensive emergency. It summarises the mechanism of action, the onset, the duration of effect, the dosing, the adverse effects and the important precautions. A hypertensive…

Levosimendan (Simdax, Simendan) in acute heart failure

…examination should be available or performed urgently to evaluate ventricular and valvular function. Levosimendan drug is generally well tolerated. Severe adverse effects are less common…

Alcohol and Cardiovascular Disease

…reflects true biological protection. Potentially favourable associations with myocardial infarction may coexist with adverse effects on stroke, heart failure, cardiovascular mortality and atrial fibrillation. Consequently…

Atrial fibrillation: ECG, classification, causes, risk factors & management

…not surprising given the adverse effects of long periods of tachycardia and desynchronized atrial and ventricular activity. Fortunately, the treatment of atrial fibrillation has come…

Bempedoic Acid: Evidence and Clinical Use

…component major adverse cardiovascular events. The reported hazard ratio was 0.83, with a 95% confidence interval of 0.72–0.95 and an absolute…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…or other circumstances that may affect cessation or treatment monitoring. Single question screening can identify unhealthy drug use requiring counselling regarding cardiovascular effects and potential…

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