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Hypertensive crisis: drugs and doses

…antihypertensive drugs used in a hypertensive emergency. It summarises the mechanism of action, the onset, the duration of effect, the dosing, the adverse effects and…

Levosimendan (Simdax, Simendan) in acute heart failure

…and thus the selection between them may be guided by individual patient needs rather than by a distinct advantage of one drug over the other…

Atrial fibrillation: ECG, classification, causes, risk factors & management

…not surprising given the adverse effects of long periods of tachycardia and desynchronized atrial and ventricular activity. Fortunately, the treatment of atrial fibrillation has come…

Adenosine for tachyarrhythmias (AVNRT, AVRT, NCT)

…or verapamil, although this is not an established drug interaction. The half life of adenosine is 8 seconds. Adverse effects are therefore very brief. Indications…

Bempedoic Acid: Evidence and Clinical Use

…component major adverse cardiovascular events. The reported hazard ratio was 0.83, with a 95% confidence interval of 0.72–0.95 and an absolute…

Smoking Cessation: Pharmacotherapy and Cardiovascular Benefit

…other circumstances that may affect cessation or treatment monitoring. Single question screening can identify unhealthy drug use requiring counselling regarding cardiovascular effects and potential drug…

Colchicine and Anti-inflammatory Therapy in Coronary Disease

…ischaemic events and possible infectious or other non cardiovascular adverse outcomes. Mechanisms of action Colchicine Colchicine appears to exert several anti inflammatory effects relevant to…

Edrophonium test

…obstruction of the bowel or the urinary tract. Marked bradycardia, sick sinus syndrome or high grade AV block without pacemaker protection. Asthma and other marked…

Alcohol and Cardiovascular Disease

…this reflects true biological protection. Potentially favourable associations with myocardial infarction may coexist with adverse effects on stroke, heart failure, cardiovascular mortality and atrial fibrillation…

Type 2 Diabetes and Cardiovascular Risk Management

…through diabetic neuropathy and adverse metabolic effects, independently of coexisting CAD, previous myocardial infarction or HF. Nevertheless, the risk of arrhythmia and sudden cardiac death…

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