…PDEI) activity, which may contribute to its inotropic profile. The drug possesses an active, acetylated metabolite with a half life exceeding 80 hours, allowing for…

…Unstable coronary artery disease. Stable angina pectoris. Secondary prophylaxis to prevent recurrence of cerebrovascular diseases, such as: Transient ischemic attacks (TIA). Stroke Contraindications Cross reactivity…

…of the Electrical Axis The heart's electrical axis represents the net vectoral sum of all active electrical wavefronts at any given point in time…

…to their indication. Do not routinely stop aspirin given as secondary prevention 8 Contact the endoscopist and the consultant on call early. In cirrhosis or…

…further reducing myocardial workload. 1 The pharmacokinetic profile of levosimendan is modulated by the presence of an active metabolite, which exerts sustained hemodynamic effects for…

…The largest relative improvement occurs when an inactive person becomes even modestly active, while additional activity continues to confer benefit with progressively smaller incremental effects…

…DICT = Drug induced cardiotoxicity Trade Name Generic/Proper Name(s) Active Ingredient(s) Cardiotoxicity Label Section DICT Concern Cardiac side effects Severity of cardiotoxicity…

…hypertensive emergency. Acute left ventricular failure. Mechanism of action Enalaprilat is the active metabolite (ester) of enalapril, an angiotensin converting enzyme (ACE) inhibitor. Enalaprilat lowers…

…a major site of disease, atherosclerosis is systemic and may affect multiple arterial territories. The arterial wall is biologically active. Endothelial and smooth muscle cells…

…clinician. The examination is typically as brief as the intervals required for rhythm checks. Achieving clear echocardiographic windows during active compressions is challenging; however, subcostal…