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In-Stent Restenosis: Mechanisms and Treatment

…ischemia and infarction Definition and Clinical Significance In stent restenosis (ISR) is recurrent narrowing within a previously implanted coronary stent. It represents a form of…

Interpretation of myocardial perfusion images (Myocardial SPECT / PET)

…specific segments of the left ventricle that demonstrate abnormalities. These tools compare perfusion data to population based reference databases, often adjusted for sex and age…

ApoB and Non-HDL Cholesterol in Cardiovascular Risk Assessment

…rather than the amount of cholesterol carried within them. Most apoB containing particles are LDL particles, with smaller contributions from VLDL, IDL, and Lp(a)…

Heart Failure With Mildly Reduced Ejection Fraction

…of LVEF, and echocardiographic measurement is subject to meaningful variability. HFmrEF may therefore represent several clinically distinct trajectories: A patient whose LVEF has improved from…

Regional Myocardial Contractile Function: Wall Motion Abnormalities

…motion abnormalities in a patient with chest pain strongly suggests myocardial ischemia as the underlying cause of the symptoms. The degree and extent of wall…

Interpretation of neonatal and pediatric electrocardiograms (ECG)

…wave U wave QT (QTc) interval Pediatric and neonatal electrocardiograms differ markedly – in terms of rhythm, morphology, normal findings, normal variants, etc – from adult electrocardiograms…

The Fourth Universal Definition of Myocardial Infarction: Types 1–5

…10–15 minutes of ischaemia. Mitochondrial abnormalities can occur even earlier after coronary occlusion and progress over time. Experimentally, necrosis advances from the subendocardium towards…

NSTEMI: Risk Stratification and Timing of the Invasive Strategy

…of myocardial necrosis, or severe ischaemia on stress testing. Such developments may convert an initially selective or delayed approach into an indication for angiography and…

Fractional shortening for estimation of ejection fraction

…value for fractional shortening (FS) Normal FS, M mode 25% Normal FS, 2D measurement 18% Advantages of fractional shortening If ventricular geometry is normal and…

Metabolic Syndrome: Definition and Clinical Significance

…syndrome is therefore both a clinical risk factor cluster and a marker of broader metabolic dysfunction. Associated abnormalities may include increased apoB and apoC III…

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