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Z16 Resistance to antimicrobial drugs
BackZ16.1Resistance to beta lactam antibioticsCategory5 →Z16.10Resistance to unspecified beta lactam antibioticsCategoryZ16.11Resistance to penicillinsCategoryZ16.12Extended spectrum beta lactamase (ESBL) resistanceCategoryZ16.13Resistance to carbapenemCategoryZ16.19Resistance to other specified beta lactam antibioticsCategoryZ16.2Resistance to other antibioticsCategory6 →Z16.20Resistance to unspecified antibioticCategoryZ16.21Resistance to vancomycinCategoryZ16.22Resistance to vancomycin related antibioticsCategoryZ16.23Resistance to quinolones and fluoroquinolonesCategoryZ16.24Resistance to multiple antibioticsCategoryZ16.29Resistance to other single specified antibioticCategoryZ16.3Resistance to other antimicrobial drugsCategory7 →Z16.30Resistance to unspecified antimicrobial drugsCategoryZ16.31Resistance to antiparasitic drug(s)CategoryZ16.32Resistance to antifungal drug(s)CategoryZ16.33Resistance to antiviral drug(s)CategoryZ16.34Resistance to antimycobacterial drug(s)Category2 →Z16.341Resistance to single antimycobacterial drugCategoryZ16.342Resistance to multiple antimycobacterial drugsCategoryZ16.35Resistance to multiple antimicrobial drugsCategoryZ16.39Resistance to other specified antimicrobial drugCategory
Category
Z16
Resistance to antimicrobial drugs
EXCLUDES
Excludes1: Methicillin resistant Staphylococcus aureus infection (A49.02)
Methicillin resistant Staphylococcus aureus pneumonia (J15.212)
Sepsis due to Methicillin resistant Staphylococcus aureus (A41.02)
Methicillin resistant Staphylococcus aureus pneumonia (J15.212)
Sepsis due to Methicillin resistant Staphylococcus aureus (A41.02)
NOTE
The codes in this category are provided for use as additional codes to identify the resistance and non-responsiveness of a condition to antimicrobial drugs.
CODING RULE
Code first: the infection
- Chapter
- XXI · Factors influencing health status and contact with health services
- Section
- Z16
- Valid from
Source
CMS ICD-10-CM Tabular List, edition FY2026.