Left main coronary artery stenosis, atherothrombotic disease, or occlusion Left main coronary artery (LMCA) occlusion is a rare but catastrophic manifestation of acute coronary syndromes.…
Introduction The traditional classification of acute coronary syndromes (ACS) into ST-segment elevation myocardial infarction (STEMI), non-STEMI (NSTEMI), and unstable angina (UA) has guided clinical decision-making…
Interpreting myocardial perfusion SPECT images involves a systematic comparison of rest and stress images to assess myocardial ischemia and infarction. The key steps in this…
Indications for myocardial perfusion imaging Contraindications for myocardial perfusion imaging Exercise stress testing is contraindicated in patients with acute myocardial infarction, unstable angina, severe aortic…
Indications for pharmacologic agents Pharmacologic stress tests are indicated in the following scenarios: Pharmacologic agents in perfusion imaging Vasodilators (adenosine, dipyridamole, regadenoson) These agents exert…
SPECT vs. PET Quantification of blood flow using PET Quantitative PET perfusion imaging offers precise measurements of myocardial blood flow in milliliters per minute per…
The ischemic cascade The ischemic cascade describes the sequence of events during myocardial ischemia, beginning with perfusion abnormalities and ultimately leading to chest pain (angina).…
Principles of myocardial perfusion imaging Myocardial perfusion imaging (MPI) is a non-invasive technique for detecting and quantifying coronary artery disease (CAD). It offers visual and…
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